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April 26, 2023
Director's Voice Blog
The 2023 Annual NIH Matilda White Riley (MWR) Behavioral and Social Sciences Honors: May 15, 2023
Now in its 16th year, the OBSSR-hosted, half-day event recognizing the legacy and relevance of Dr. Matilda White Riley's work in the field of behavioral and social sciences will be held using a virtual format on Monday, May 15, 2023, from 1:30 to 4:45 p.m. ET.
It is OBSSR’s honor to recognize Dr. Jennifer J. Manly as the 2023 Distinguished Lecturer. Jennifer J. Manly, Ph.D., is a Professor of Neuropsychology in the Department of Neurology at Columbia University Irving Medical Center. Her research focuses on mechanisms of inequalities in cognitive aging and Alzheimer’s Disease. Her research team has partnered with the Black and Latinx communities in New York City and around the United States to design and carry out investigations of structural and social forces across the lifecourse, such as educational opportunities, discrimination, and socioeconomic inequality, and how these factors relate to cognition and brain health later in life.
Behavioral and Social Sciences Research Spotlights
Parental monitoring may moderate the associate between childhood environmental risk and adverse health outcomes into adulthood
Characteristics of early childhood environments are known to be associated with health trajectories over the lifespan. While adverse home environments and risky neighborhood environments are strongly linked with adverse physical and mental health outcomes as children age, a growing body of research has shown that certain parenting behaviors, such as parental monitoring, knowledge of children’s’ daily lives, and limit- or boundary-setting can have a moderating effect for at-risk youth. The discussion of parental monitoring has become more nuanced within the past two decades. If children are living in risky environments, heightened parental vigilance has been shown to be associated with fewer negative mental and physical health outcomes into adolescence and beyond. However, in lower-risk (and higher resourced) environments, this protective relationship has not been observed. In fact, in these lower-risk settings, parental monitoring and limit-setting may be associated with poor outcomes in youth. Recently published research supported by the NIH Common Fund, NIMHD, and others aimed to address this knowledge gap, by investigating longitudinal associations between early childhood environments, parental vigilance, and adult physical and mental health outcomes.
In Sub-Saharan Africa, structural biases and legal barriers might contribute to higher HIV prevalence among MSM
It is widely accepted that men who have sex with men (MSM) are adversely impacted by HIV, due to the role of public and private stigma that influence barriers to HIV prevention, diagnosis, and social support. However, there is a paucity of research investigating the associations between discriminatory public policies and structural biases and health outcomes impacting the MSM and LGBTQ communities. Supported by NIMH, NIAID, and others, researchers leveraged pooled, cross-sectional study data to conduct multilevel logistic regression to further the science regarding these associations.
Corporal punishment may impact neural systems to produce negative behavioral effects in adolescence
Decades of research has indicated that corporal punishment, defined as the use of physical pain to punish, correct, discipline, etc., can evoke a complex emotional experience in adolescents including increased anxiety, depressive symptoms, we well as increased aggressive and antisocial behavior and reduced inhibitory control and working memory capacity. Additionally, harsh parenting, characterized by high levels of control and low levels of warmth and can include corporal punishment may influence how the child’s brain responds to mistakes. Despite this previous research, the effect of corporal punishment on neurocognitive systems is not fully understood. A new study supported by NIMH and others investigated the neural mechanisms underlying the association between corporal punishment and these adverse effects.
News and Events
Register: Dr. Jennifer J. Manly and ESI Honorees on May 15

16th NIH Matilda White Riley Behavioral and Social Sciences Honors (virtual event)
Monday, May 15, 2023, 1:30 p.m. to 4:45 p.m. ET
Register and view the agenda: https://www.scgcorp.com/thmwrhonors2023
2023 NIH Matilda White Riley (MWR) Distinguished Lecturer:
Jennifer J. Manly, Ph.D., Professor, Columbia University Irving Medical Center
Presenting: Lifecourse Social and Structural Mechanisms of Inequalities in Cognitive Aging and Alzheimer’s Disease
2023 NIH MWR Paper Competition Early-Stage Investigator Honorees

Developing and applying a novel natural language processing approach to characterize violent deaths in the National Violent Death Reporting System (NVDRS)
Alina Arseniev-Koehler, Ph.D.
University of California San Diego
Psychosocial-behavioral phenotyping and beyond: Biomedical informatics methods for precision behavioral nutrition
Marissa Burgermaster, Ph.D.
The University of Texas at Austin
Cognability: An ecological theory of neighborhoods and cognitive aging
Jessica Finlay, Ph.D.
University of Michigan
Investigating biological pathways underpinning the longitudinal association between loneliness and incident cognitive impairment
Ted K.S. Ng, Ph.D.
Arizona State University
OBSSR Director's Webinar with Dr. Megan L. Ranney on May 16

Violence as a public health problem: What we know, and where we are going
May 16, 2023, 2:00 – 3:00 p.m. ET
Register: https://scgcorp.zoom.us/webinar/register/WN_qDH0nIIMRce4QKypVHUqEQ#/registration
Featured Plenary Speaker:
Megan L. Ranney, MD, MPH, FACEP, Deputy Dean, Brown University School of Public Health
Overview
The United States had more mass shootings than days of the year in 2022, and firearm injury has overtaken car crashes as the leading cause of death for American children. Meanwhile, our youth — particularly young women and sexual- and gender-minority youth — are reporting unprecedented rates of depression and suicidal thoughts. In this talk, Dr. Ranney will present work that illuminates the current state of knowledge on physical, digital, and firearm violence and co-occurring disorders (such as depressive symptoms and substance use disorder). She will discuss novel approaches, drawn from her and others’ work, to studying, preventing, and treating these interdependent crises across the social-ecological model. Attendees will leave with clarity on what we know, what we don’t know, and where we need to move faster.
Ableism in Medicine and Clinical Research
Dates: April 27 & 28, 2023
Location: NIH Videocast
This two-day, virtual workshop hosted by NIH, focuses on awareness and research opportunities to mitigate the impact of Ableism in both clinical care and the biomedical and behavioral research enterprise.
The scientific sessions during this workshop will focus on Ableism across multiple dimensions, including:
- Ableism as a barrier to clinical care and a contributor to health disparities experienced by People with Disabilities.
- Ableism in the biomedical and behavioral scientific workforce and graduate education system.
- Accessibility in biomedical and behavioral research.
- Research opportunities addressing structural and cultural barriers created by Ableism.
This workshop is intended to inform future research areas in this complex area of public health.
Workshop on Brain Behavior Quantification and Synchronization: Sensor Technologies to Capture the Complexity of Behavior
Dates: May 2–3, 2023
Location: Hybrid — NIH Campus, Natcher Auditorium, Bethesda, Maryland and Virtual
As a part of the National Institutes of Health’s Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative's Brain Behavior Quantification and Synchronization Program, the National Institute of Mental Health is conducting a workshop on sensor technologies to improve our understanding of complex behavior.
The goal of this workshop is to bring together a diverse group of scientists and innovators from various fields and sectors to improve our understanding of behavior in health and disease. This event is free and registration is required. Onsite registration is available, but if attendees want lunch, you must register in advance.
Webinar Recording Available: Re-imagining What’s Possible: A Future Where Reproductive Justice is Achieved
On March 28, 2023, OBSSR hosted a director's webinar featuring Dr. Monica McLemore on “Re-imagining What’s Possible: A Future Where Reproductive Justice is Achieved.” The purpose of this session was to honor the work that has been done toward health equity and to move beyond reproductive health and rights to reproductive justice. Dr. McLemore is a tenured professor in the Child, Family, and Population Health Department and the Interim Director for the Center for Anti-Racism in Nursing at the University of Washington School of Nursing.
NIH Institutional Excellence in Diversity, Equity, Inclusion, and Accessibility in Biomedical and Behavioral Research Prize Competition
NIH is now accepting submissions for a new initiative that rewards effective strategies for enhancing diversity, equity, inclusion, and accessibility (DEIA) in research environments: the NIH Institutional Excellence in Diversity, Equity, Inclusion, and Accessibility (DEIA) in Biomedical and Behavioral Research Prize Competition.
The prize competition will recognize and reward biomedical and behavioral science institutions that have identified gaps in DEIA and designed, implemented, and evaluated interventions to address them. It also aims to identify effective practices for enhancing DEIA within faculty, postdoctoral scholars, and student bodies that can be feasibly disseminated for adoption by other institutions.
NIH will award up to 10 prizes of $100,000 each through the competition. Up to half of the prizes will be set aside for consideration for limited-resourced institutions. NIH may also recognize additional entries as honorable mentions with nonmonetary awards.
Prospective applicants are strongly encouraged to attend the prize competition preregistration webinar on May 17, 2023.
Visit the Prize Competition website to review the eligibility and participation rules and to submit a written entry. The deadline to apply is September 26, 2023.
NIH Releases FY 2023-2027 NIH-Wide Strategic Plan for DEIA
The National Institutes of Health recently issued its Fiscal Years 2023-2027 NIH-Wide Strategic Plan for Diversity, Equity, Inclusion, and Accessibility (DEIA). Harmonized with the 2021-2025 NIH-Wide Strategic Plan, the plan articulates NIH’s commitment to embracing, strengthening, and integrating DEIA across all agency activities. The plan will guide actions across the agency in a transparent and accountable manner to achieve NIH’s vision of being a people-centered organization where all feel a sense of belonging when advancing the NIH mission.
The plan organizes NIH’s DEIA priorities in three key areas or objectives to address DEIA in NIH’s operations, its workforce, and in the research it supports. Across all these priorities, NIH emphasizes three crosscutting themes—promoting transparency, communication, and engagement; fostering sustainable change; and harnessing data.
PATH Study: Wave 6 Data Release
The Population Assessment of Tobacco and Health (PATH) Study announces the release of the Wave 6 Restricted-Use File (RUF), an updated Master Linkage File, and updates to the Restricted Use Files to include Ever/Never Reference Data from Wave 5.5 and the PATH Study Adult Telephone Survey (PATH ATS). Wave 6 files contain data collected through the PATH Study (March 2021 through November 2021), and researchers may apply for access at https://doi.org/10.3886/ICPSR36231. In addition to applying for access to the Restricted-Use Files, members of the research community are encouraged to apply for the Biomarker Restricted-Use Files at https://doi.org/10.3886/ICPSR36840. The Biospecimen Access Program webpage provides information on how to access the urine, serum, plasma, and genomic DNA (gDNA) collected from adult PATH Study participants during Wave 1 (2013 – 2014) and urine collected during Wave 2 (2014 – 2015), Wave 3 (2015-2016), Wave 4 (2016-2018), and Wave 5 (2018-2019). Public-Use Files are also available for download at https://doi.org/10.3886/ICPSR36498. The updated Master Linkage Files for the PATH Study may be downloaded from https://doi.org/10.3886/ICPSR38008.
Information about the PATH Study can be found in the “For Researchers” section of the PATH Study Series Page at https://doi.org/10.3886/Series606
Recently Published Funding Announcements
Notice of Special Interest: Administrative Supplements to NIH-funded T32 and TL1 Training Grants to Better Integrate Behavioral and Social Sciences (BSS) with other Health-Related Sciences Disparities
Notice Number
NOT-OD-23-098
Key Dates
First Available Due Date: May 1, 2023
Expiration Date: May 2, 2023
Purpose
OBSSR is interested in supporting the integration of health-related behavioral and social sciences (BSS) with other biomedical methodological and scientific disciplines (e.g., genetics, immunology, metabolomics, molecular biology, microbiome, biochemistry, or physiological sciences). The goal is to train a research workforce that has the integrated content expertise and skills to meaningful address gaps in scientific advancement that are not well served by a more siloed approach to research.
Notice of Intent to Publish a Funding Opportunity Announcement for Accelerating Behavioral and Social Science through Ontology Development and Use (U01)
NOFO Number
NOT-OD-23-089
Key Dates
Estimated Publication Date of Funding Opportunity : April 30, 2023
First Estimated Application Due Date: September 30, 2023
Purpose
OBSSR, with other NIH Institutes and Centers (ICs), intends to promote a new initiative by publishing a funding opportunity to accelerate behavioral and social science through ontology development and use. Applications will be encouraged to develop new or expand existing ontologies for behavioral or social science research (BSSR). Applicants will be expected to form multi-disciplinary teams including subject matter experts in one or more BSSR fields, as well as experts in semantic knowledge structures. Proposals will be expected to focus on health-relevant terminology related to constructs, measures, and/or interventions. Funded projects and investigator teams will participate in a collaborative research network. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The funding opportunities are expected to be published in Spring 2023 with expected application due dates in Fall 2023.
Research projects supported should focus on behavioral or social science ontology expansion or development, dissemination, and use. The projects must include multidisciplinary teams of subject-matter experts in behavioral and/or social science as well as ontology related informatics. Each project should identify one or more use cases and elucidate the justification of the need and potential demand for the proposed ontological resource or tool. Examples of use cases include, but are not limited to, those listed in Ontologies in the Behavioral Sciences: Accelerating Research and the Spread of Knowledge. Projects should advance research capabilities and efficiencies and address problems not easily solved without improvement in semantic knowledge structures (e.g., controlled vocabularies, taxonomies, and ontologies).
Notice of Intent to Publish a Funding Opportunity Announcement for Accelerating Behavioral and Social Science through Ontology Development and Use (U24)
NOFO Number
NOT-OD-23-090
Key Dates
Estimated Publication Date of Funding Opportunity: April 30, 2023
First Estimated Application Due Date: September 30, 2023
Purpose
OBSSR, with other NIH Institutes and Centers (ICs), intends to publish a funding opportunity soliciting applications to establish a Dissemination and Coordination Center (DCC) for a U24 Research Network on Behavioral and Social Science Ontology Development. DCC teams must include subject matter experts in one or more fields of behavioral or social science, ontology-related informatics and computational approaches, and Team Science or the Science of Science.
The DCC supported through this initiative will have four primary responsibilities: 1) Coordinating and providing logistical support to facilitate collaboration and cross-U01 project learning; 2) Providing ontology-related technical, computational, and informatics expertise and support; 3) Facilitating dissemination of resources and training to support ontology expansion, development, and use; and 4) Providing active outreach and coordination with relevant stakeholders to increase understanding of and demand for BSSR ontology-related tools and resources.
BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Basic Experimental Studies with Humans Required)
NOFO Number
RFA-DC-24-001
Key Dates
Open Date (Earliest Submission Date): August 22, 2023
Expiration Date: September 20, 2025
Purpose
Invasive surgical procedures offer the opportunity for unique intracranial interventions such as the ability to record and stimulate intracranially within precisely localized brain structures in humans. Human studies using invasive technology are often constrained by a limited number of patients and available resources, and frequently the resulting datasets need to be aggregated across sites to achieve sufficient statistical power. To overcome these fundamental barriers and to investigate high-impact questions in human neuroscience, this NOFO seeks applications to assemble diverse, integrated, multi-disciplinary teams that cross boundaries of interdisciplinary collaboration.
BRAIN Initiative Fellows: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)
NOFO Number
RFA-MH-23-110
Key Dates
Open Date (Earliest Submission Date): July 9, 2023
Expiration Date: August 12, 2025
Purpose
The purpose of the Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative Fellows (F32) program is to enhance the research training of promising postdoctorates early in their postdoctoral training period, who have the potential to become productive investigators in research areas that will advance the goals of the BRAIN Initiative. Applications are encouraged in any research area aligned with the BRAIN Initiative, including neuroethics.
Notice of Special Interest (NOSI): Research to Address Vaccine Uptake and Implementation among Populations Experiencing Health Disparities
NOSI Number
NOT-MD-23-008
Key Dates
First Available Due Date: May 17, 2023
Expiration Date: June 6, 2026
Purpose
This NOSI highlights the need for research on strategies and interventions to increase vaccine uptake and implementation among populations experiencing health disparities in the United States (U.S.) and its territories.
Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)
NOFO Number
PAR-23-138
Key Dates
Open Date (Earliest Submission Date): June 3, 2023
Expiration Date: June 3, 2025
Purpose
The Instrumentation Grant Program for Resource-limited Institutions supports the purchase of state-of-the-art scientific instruments to enhance the research and educational missions of resource-limited institutions. Requested instruments may support biomedical research and education in basic, translational, biomedically-related behavioral or clinical fields.
Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32 Clinical Trial Not Allowed)
NOFO Number
PAR-22-265
Key Dates
Open Date (Earliest Submission Date): April 25, 2023
Expiration Date: May 26, 2025
Purpose
The Jointly Sponsored NIH Predoctoral Training Program in the Neurosciences (JSPTPN) is an institutional program that supports broad and fundamental research training in the neurosciences. In addition to a broad education in the neurosciences, a key component will be a curriculum that provides a strong foundation in experimental design, statistical methodology and quantitative reasoning. JSPTPN programs are intended to be 2 years in duration and students may only be appointed to this training grant during the first 2 years of their graduate research training. The primary objective is to prepare students to be well-trained scientists equipped to pursue careers in neuroscience.
BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
NOFO Number
RFA-NS-24-005
Key Dates
Open Date (Earliest Submission Date): May 30, 2023
Expiration Date: January 21, 2026
Purpose
This funding opportunity seeks applications to optimize instrumentation and device technologies for recording and modulation of neural cells and circuits, to address major challenges and to enable transformative understanding of dynamic signaling in the central nervous system. It is expected that the proposed technologies and approaches have previously demonstrated their transformative potential through initial proof-of-concept testing, and are ready for accelerated refinement through iterative engineering and end-user feedback, appropriate for a path towards sustainable dissemination and user-friendly incorporation into routine neuroscience research.
BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
NOFO Number
RFA-NS-24-004
Key Dates
Open Date (Earliest Submission Date): May 30, 2023
Expiration Date: January 21, 2026
Purpose
This funding opportunity seeks applications for proof-of-concept testing and development of new technologies and novel approaches for recording and modulation of neural cells and circuits, to address major challenges and enable transformative understanding of dynamic signaling in the central nervous system. Preliminary feasibility data are not required, and it is expected that the proposed research may be high-risk, but if successful could profoundly change the course of neuroscience research.
Research With Activities Related to Diversity (ReWARD) (R01 Clinical Trial Optional)
NOFO Number
PAR-23-122
Key Dates
Open Date (Earliest Submission Date): May 5, 2023
Expiration Date: May 8, 2026
Purpose
The NIH Research With Activities Related to Diversity (ReWARD) Program's overarching goal is to enhance the breadth and geographical location of research and research-related activities supported by NIH. The ReWARD program provides support for the health-related research of scientists who are making a significant contribution to Diversity, Equity, Inclusion, and Accessibility (DEIA) and who have no current NIH research project grant funding. The ReWARD program provides funding for both the scientific research and the DEIA activities of investigators. The grant will support scientific research in areas related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) and ongoing DEIA activities focused on enhancing diversity in the biomedical research enterprise within the United States and territories.
BSSR Accomplishments
The NIH has been an instrumental leader in shaping and supporting behavioral and social sciences research (BSSR) to improve the nation’s health. Integrated with advances in other scientific disciplines, BSSR has made substantial contributions to the prevention or treatment of numerous physical health and mental health conditions.
In collaboration with subject matter experts from Institutes, Centers, and Offices across NIH, OBSSR has summarized some of the important scientific advances that demonstrate the valuable contribution of BSSR across various health conditions and behaviors. These summaries are provided as fact sheets (PowerPoint slides forthcoming) that highlight a significant public health problem and the corresponding BSSR-informed approaches used to address the problem. Various audiences such as academic researchers, public health organizations, and other health federal agencies, may find these materials useful to demonstrate to their stakeholders the importance of BSSR to the health of the United States population.
These new BSSR accomplishment resources are available on the OBSSR website:
Improving Sleep
Managing Chronic Pain
Preventing and Treating Diabetes
Preventing Intimate Partner Violence
Reducing Teen Pregnancy
Reducing Tobacco Use
Treating Depression
Treating Obsessive-Compulsive Disorder
Treating Phobias
Treating Post-Traumatic Stress Disorder
Additional BSSR accomplishments will be added to the website in 2023.
BSSR Clinical Trials Resources
CLINICAL TRIALS PROTOCOL TEMPLATE FOR THE BEHAVIORAL AND SOCIAL SCIENCES
The Clinical Trials Protocol Template for the Behavioral and Social Sciences is a resource for communicating the science, methods, and operations of a clinical trial. This template is a suggested format for clinical trials that are testing a behavioral or social intervention or experimental manipulation. Use of the protocol template is encouraged but not required.
The Behavioral and Social Clinical Trials Template was derived from the successful NIH-FDA Phase 2/3 IND-IDE Clinical Trial Template but was adapted to include terminology and approaches used by behavioral and social scientists.
While the template is a suggested format for clinical trials that are testing a behavioral or social intervention or manipulation for which a stand-alone clinical protocol is required, the template can also be a useful tool for those trials funded by NIH Institutes or Centers that do not require stand-alone clinical protocols. Using the template to anticipate decision points and potential challenges before a study launches can help avoid subsequent delays and problems.
DECISION SUPPORT TOOL: FEATURES TO CONSIDER IN DETERMINING IF A CLINICAL TRIAL IS PHASE II OR PHASE III
This document is the result of a working group led by OBSSR, with participants from other Institutes, Centers, and Offices. It is a designed to be a resource to help investigators, program officers, and reviewers determine if a behavioral or social science study is better characterized as a Phase II or a Phase III clinical trial. Distinguishing earlier phases of clinical trials (Phase 0 or I) is not usually difficult but distinguishing between a Phase II and III study can be more challenging, particularly for non-drug trials. Being thoughtful about this distinction is important for a variety of reasons, not least of which is that a Phase III designation for an NIH funded clinical trial generally requires following additional policies and practices beyond those that already apply to Phase II clinical trials, such as the requirement for valid analysis and for a Data and Safety Monitoring Board (DSMB).
PHASE III TRIALS
NIH’s definition of a Phase III Clinical Trial is quite broad, including drug studies, device studies, behavioral interventions, epidemiological studies, community trials, and more. Phase III trials are usually large, prospective trials that compare two or more interventions against other standard or experimental interventions. In this next episode of our NIH All About Grants podcast (MP3 / Transcript) we explain what a Phase III trial is, how it compares to other types of clinical trials, considerations for your application and its review, how these studies influence standards of care, helpful tools and other resources, and much more. The guests include Ms. Dawn Corbett, NIH’s Inclusion Policy Officer, and Dr. Christine Hunter, former OBSSR Acting Director.
Social and Behavioral Good Clinical Practice eCourse
In September 2016, the NIH issued a Policy on Good Clinical Practice (GCP) Training for NIH Awardees Involved in NIH-funded Clinical Trials. GCP is an international ethical and scientific quality standard for designing, conducting, recording and reporting clinical trials. The principles of GCP help assure the safety, integrity, and quality of clinical trials. Investigators and clinical trial staff who are competent in GCP principles will be better able to assure that the rights, safety, and well-being of human subjects are protected; that clinical trials are conducted in accordance with approved plans and with rigor and integrity; and that data derived from clinical trials are reliable.
Extramural Researchers can go here to take the course.
NIH Employees can go here to take the course. (NIH login required)
Educational Facilities can Download the Good Clinical Practices for Social and Behavioral Sciences Course for your educational facility's Learning Management System (LMS).

